Botulinum toxin is a protein that was produced by the bacterium Clostridium botulinum and is considered the most powerful neurotoxin ever discovered. Botulinum toxin causes botulism poisoning, a severe and life threatening disease in humans and in monkeys animals.When introduced intravenously, type A (Botox Cosmetic) of the toxin has an LD50 of 40-56 ng, about 32 ng type C1, type D 3200 ng and type E 88 ng, so that the above-mentioned types, some of the most powerful neurotoxins known known.Popularly by its trade name, Botox or Dysport, it is used for various cosmetic and medical procedures.
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Minggu, 10 Juli 2011
Botulinum | Botulinum Toxin
Sabtu, 09 Juli 2011
Botox Cosmetics Description
DESCRIPTION
BOTOX® Cosmetics (onabotulinumtoxinA) for injection, is a vacuum, dry sterile purified botulinum toxin type A, produced from fermentation of Hall strain Clostridium botulinum type A grown in medium containing casein hydrolyzate, glucose, and yeast extract, is intended to intramuscular use. It is purified from the culture solution by dialysis and a series of acid precipitations to a complex consisting of the neurotoxin and several accessory proteins. The complex dissolved in a solution of sodium chloride containing sterile human albumin and sterile filtered (0.2 microns) prior to filling and vacuum drying.
One Unit of BOTOX® Cosmetics according to the median lethal intraperitoneal calculated Dose (LD 50
) In mice. The method used to perform testing that is specific to Allergan
BOTOX® Cosmetics (onabotulinumtoxinA) for injection, is a vacuum, dry sterile purified botulinum toxin type A, produced from fermentation of Hall strain Clostridium botulinum type A grown in medium containing casein hydrolyzate, glucose, and yeast extract, is intended to intramuscular use. It is purified from the culture solution by dialysis and a series of acid precipitations to a complex consisting of the neurotoxin and several accessory proteins. The complex dissolved in a solution of sodium chloride containing sterile human albumin and sterile filtered (0.2 microns) prior to filling and vacuum drying.
One Unit of BOTOX® Cosmetics according to the median lethal intraperitoneal calculated Dose (LD 50
) In mice. The method used to perform testing that is specific to Allergan
Label:
Botox Cosmetic,
Botoxs,
botulinum toxin,
What Is Botox
Kamis, 07 Juli 2011
Botox Side Efects
Side effects that usually mild and transient, can be predicted from the mode of action (muscle paralysis) and chemical structure (protein) of the molecule, which by and large in two major areas of side effects: paralysis of the wrong muscle group and allergic reaction. Bruising at the injection site is not a side effect of the poison, but the mode of administration. In cosmetic use, this in an inappropriate facial expression such as drooping eyelid, double vision, uneven smile, or the loss of the ability to close your eyes cause. This will subside in about six weeks. Bruising by the clinician to prevent pressure on the puncture site can occur but still, and will take about 7-10 days. When injecting the Master muscle of the jaw, loss of muscle function in a loss or reduction of power will lead to chew solid food. All cosmetic treatments are of limited duration and can be as short a period to six weeks, but usually we see an effective period of between three and eight months. Is used at the extremely low doses of medicine, has a very low toxicity of botulinum toxin.
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